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The Impact of Chronic Mild Stress and Agomelatine Treatment on the Expression Level and Methylation Status of Genes Involved in Tryptophan Catabolic Pathway in PBMCs and Brain Structures

Depression is the serious mental disorder. Previous studies suggest that the development mechanism of depression may be associated with disorders of the tryptophan catabolic pathway (TRYCAT). Thus, this study investigates the effect of agomelatine treatment on the expression and methylation status o...

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Detalles Bibliográficos
Autores principales: Wigner, Paulina, Synowiec, Ewelina, Jóźwiak, Paweł, Czarny, Piotr, Białek, Katarzyna, Bijak, Michal, Szemraj, Janusz, Gruca, Piotr, Papp, Mariusz, Sliwinski, Tomasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563711/
https://www.ncbi.nlm.nih.gov/pubmed/32962062
http://dx.doi.org/10.3390/genes11091093