Optimized Hepatitis C Virus (HCV) E2 Glycoproteins and their Immunogenicity in Combination with MVA-HCV

Hepatitis C virus (HCV) represents a major global health challenge and an efficient vaccine is urgently needed. Many HCV vaccination strategies employ recombinant versions of the viral E2 glycoprotein. However, recombinant E2 readily forms disulfide-bonded aggregates that might not be optimally suit...

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Detalles Bibliográficos
Autores principales: Marín, María Q., Sliepen, Kwinten, García-Arriaza, Juan, Koekkoek, Sylvie M., Pérez, Patricia, Sorzano, Carlos Óscar S., Gómez, Carmen E., Sanders, Rogier W., Esteban, Mariano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563715/
https://www.ncbi.nlm.nih.gov/pubmed/32764419
http://dx.doi.org/10.3390/vaccines8030440

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563715/
https://www.ncbi.nlm.nih.gov/pubmed/32764419
http://dx.doi.org/10.3390/vaccines8030440

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