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Effects of Protein Unfolding on Aggregation and Gelation in Lysozyme Solutions

In this work, we investigate the role of folding/unfolding equilibrium in protein aggregation and formation of a gel network. Near the neutral pH and at a low buffer ionic strength, the formation of the gel network around unfolding conditions prevents investigations of protein aggregation. In this s...

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Detalles Bibliográficos
Autores principales: Nikfarjam, Shakiba, Jouravleva, Elena V., Anisimov, Mikhail A., Woehl, Taylor J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563771/
https://www.ncbi.nlm.nih.gov/pubmed/32887233
http://dx.doi.org/10.3390/biom10091262