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6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase Suppresses Neuronal Apoptosis by Increasing Glycolysis and “cyclin-dependent kinase 1-Mediated Phosphorylation of p27 After Traumatic Spinal Cord Injury in Rats

Apoptosis is a vital pathological factor that accounts for the poor prognosis of traumatic spinal cord injury (t-SCI). The 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFKFB3) is a critical regulator for energy metabolism and proven to have antiapoptotic effects. This study aimed to investi...

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Detalles Bibliográficos
Autores principales: Gao, Liansheng, Wang, Chun, Qin, Bing, Li, Tao, Xu, Weilin, Lenahan, Cameron, Ying, Guangyu, Li, Jianru, Zhao, Tengfei, Zhu, Yongjian, Chen, Gao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563815/
https://www.ncbi.nlm.nih.gov/pubmed/32841050
http://dx.doi.org/10.1177/0963689720950226