Cargando…

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase Suppresses Neuronal Apoptosis by Increasing Glycolysis and “cyclin-dependent kinase 1-Mediated Phosphorylation of p27 After Traumatic Spinal Cord Injury in Rats

Apoptosis is a vital pathological factor that accounts for the poor prognosis of traumatic spinal cord injury (t-SCI). The 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFKFB3) is a critical regulator for energy metabolism and proven to have antiapoptotic effects. This study aimed to investi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gao, Liansheng, Wang, Chun, Qin, Bing, Li, Tao, Xu, Weilin, Lenahan, Cameron, Ying, Guangyu, Li, Jianru, Zhao, Tengfei, Zhu, Yongjian, Chen, Gao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563815/ https://www.ncbi.nlm.nih.gov/pubmed/32841050 http://dx.doi.org/10.1177/0963689720950226

Ejemplares similares

Phosphofructo-2-kinase/Fructose-2,6-bisphosphatase Modulates Oscillations of Pancreatic Islet Metabolism
por: Merrins, Matthew J., et al.
Publicado: (2012)

Balancing glycolytic flux: the role of 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatases in cancer metabolism
por: Ros, Susana, et al.
Publicado: (2013)

The role of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 in esophageal squamous cell carcinoma
por: Bao, Junhui, et al.
Publicado: (2020)

Liver X Receptor α Is Involved in the Transcriptional Regulation of the 6-Phosphofructo-2-Kinase/Fructose-2,6-Bisphosphatase Gene
por: Zhao, Li-Feng, et al.
Publicado: (2012)

Increased expression and phosphorylation of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase isoforms in urinary exosomes in pre-eclampsia
por: Ellis, R., et al.
Publicado: (2019)

6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase isoform 3 spatially mediates autophagy through the AMPK signaling pathway
por: Yan, Siyuan, et al.
Publicado: (2017)

Expression of Alternative Splice Variants of 6-Phosphofructo-2-kinase/Fructose-2,6-bisphosphatase-4 in Normoxic and Hypoxic Melanoma Cells
por: Trojan, Sonia E., et al.
Publicado: (2021)

Fructose-2,6-Bisphosphate synthesis by 6-Phosphofructo-2-Kinase/Fructose-2,6-Bisphosphatase 4 (PFKFB4) is required for the glycolytic response to hypoxia and tumor growth
por: Chesney, Jason, et al.
Publicado: (2014)

Partial Inhibition of the 6-Phosphofructo-2-Kinase/Fructose-2,6-Bisphosphatase-3 (PFKFB3) Enzyme in Myeloid Cells Does Not Affect Atherosclerosis
por: Tillie, Renée J. H. A., et al.
Publicado: (2021)

Identification of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFKFB4) as a Novel Autophagy Regulator by High Content shRNA Screening
por: Strohecker, Anne M., et al.
Publicado: (2015)

Glucagon induces translocation of glucokinase from the cytoplasm to the nucleus of hepatocytes by transfer between 6-phosphofructo 2-kinase/fructose 2,6-bisphosphatase-2 and the glucokinase regulatory protein
por: Cullen, Kirsty S., et al.
Publicado: (2014)

Dry-milled flour rice ‘Seolgaeng’ harbors a mutated fructose-6-phosphate 2-kinase/fructose-2,6-bisphosphatase2
por: Kang, Ju-Won, et al.
Publicado: (2023)

6-Phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 and 4: A pair of valves for fine-tuning of glucose metabolism in human cancer
por: Yi, Mei, et al.
Publicado: (2018)

Monocarboxylate transporter 1 promotes classical microglial activation and pro-inflammatory effect via 6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 3
por: Kong, Liang, et al.
Publicado: (2019)

Protein Kinase CK2 Contributes to Glucose Homeostasis by Targeting Fructose-1,6-Bisphosphatase 1
por: Pack, Mandy, et al.
Publicado: (2022)

Decreased fructose-1,6-bisphosphatase-2 expression promotes glycolysis and growth in gastric cancer cells
por: Li, He, et al.
Publicado: (2013)

Fructose 1,6-bisphosphatase: getting the message across
por: Timson, David J.
Publicado: (2019)

Evolution of Allosteric Citrate Binding Sites on 6-phosphofructo-1-kinase
por: Usenik, Aleksandra, et al.
Publicado: (2010)

Fructose-1, 6-bisphosphatase opposes renal carcinoma progression
por: Li, Bo, et al.
Publicado: (2014)

Posttranslational Modification of 6-phosphofructo-1-kinase as an Important Feature of Cancer Metabolism
por: Šmerc, Andreja, et al.
Publicado: (2011)

Small molecule inhibition of 6-phosphofructo-2-kinase suppresses t cell activation
por: Telang, Sucheta, et al.
Publicado: (2012)

Amylin deposition activates HIF1α and 6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 3 (PFKFB3) signaling in failing hearts of non-human primates
por: Liu, Miao, et al.
Publicado: (2021)

The Role of Liver Fructose-1,6-Bisphosphatase in Regulating Appetite and Adiposity
por: Visinoni, Sherley, et al.
Publicado: (2012)

A Chinese Adult Patient with Fructose 1,6-bisphosphatase Deficiency
por: Lu, Jing-Ru, et al.
Publicado: (2017)

Clinical and Molecular Characterization of Patients with Fructose 1,6-Bisphosphatase Deficiency
por: Li, Niu, et al.
Publicado: (2017)

Regulation of Fructose 1,6-Bisphosphatase in Procyclic Form Trypanosoma brucei
por: Wilkinson, Christina, et al.
Publicado: (2021)

KLF9 (Kruppel Like Factor 9) induced PFKFB3 (6-Phosphofructo-2-Kinase/Fructose-2, 6-Biphosphatase 3) downregulation inhibits the proliferation, metastasis and aerobic glycolysis of cutaneous squamous cell carcinoma cells
por: Xing, Jiahua, et al.
Publicado: (2021)

Vid24p, a Novel Protein Localized to the Fructose-1,6-bisphosphatase–containing Vesicles, Regulates Targeting of Fructose-1,6-bisphosphatase from the Vesicles to the Vacuole for Degradation
por: Chiang, Meng-Chieh, et al.
Publicado: (1998)

Inhibition of 6-phosphofructo-2-kinase (PFKFB3) induces autophagy as a survival mechanism
por: Klarer, Alden C, et al.
Publicado: (2014)

Cell cycle-dependent expression and subcellular localization of fructose 1,6-bisphosphatase
por: Mamczur, Piotr, et al.
Publicado: (2011)

Metformin reduces liver glucose production by inhibition of fructose-1-6-bisphosphatase
por: Hunter, Roger W., et al.
Publicado: (2018)

Expression, regulation and function of phosphofructo-kinase/fructose-biphosphatases (PFKFBs) in glucocorticoid-induced apoptosis of acute lymphoblastic leukemia cells
por: Carlet, Michela, et al.
Publicado: (2010)

The role of fructose-1,6-bisphosphatase 1 in abnormal development of ovarian follicles caused by high testosterone concentration
por: Liu, Tao, et al.
Publicado: (2017)

Regulation by S-nitrosylation of the Calvin-Benson cycle fructose-1,6-bisphosphatase in Pisum sativum
por: Serrato, Antonio Jesús, et al.
Publicado: (2017)

Identification of genotype–biochemical phenotype correlations associated with fructose 1,6-bisphosphatase deficiency
por: Sakuma, Ikki, et al.
Publicado: (2023)

6-Phosphofructo-2-kinase (PFKFB3) promotes cell cycle progression and suppresses apoptosis via Cdk1-mediated phosphorylation of p27
por: Yalcin, A, et al.
Publicado: (2014)

The independent prokaryotic origins of eukaryotic fructose-1, 6-bisphosphatase and sedoheptulose-1, 7-bisphosphatase and the implications of their origins for the evolution of eukaryotic Calvin cycle
por: Jiang, Yong-Hai, et al.
Publicado: (2012)

Simultaneous inhibition of the estrogen receptor and 6-phosphofructo-2-kinase (PFKFB3) for the treatment of ER+ breast cancer
por: Imbert-Fernandez, Yoannis, et al.
Publicado: (2014)

Overexpression of a modified 6-phosphofructo-1-kinase results in an increased itaconic acid productivity in Aspergillus niger
por: van der Straat, Laura, et al.
Publicado: (2013)

Targeting the sugar metabolism of tumors with a first-in-class 6-phosphofructo-2-kinase (PFKFB4) inhibitor
por: Chesney, Jason, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_8tmb5dchcou2sqvpie67r3s4pl