BV-2 Microglial Cells Respond to Rotenone Toxic Insult by Modifying Pregnenolone, 5α-Dihydroprogesterone and Pregnanolone Levels

Neuroinflammation, whose distinctive sign is the activation of microglia, is supposed to play a key role in the development and progression of neurodegenerative diseases. The aim of this investigation was to determine levels of neurosteroids produced by resting and injured BV-2 microglial cells. BV-...

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Detalles Bibliográficos
Autores principales: Avallone, Rossella, Lucchi, Chiara, Puja, Giulia, Codeluppi, Alessandro, Filaferro, Monica, Vitale, Giovanni, Rustichelli, Cecilia, Biagini, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563827/
https://www.ncbi.nlm.nih.gov/pubmed/32933155
http://dx.doi.org/10.3390/cells9092091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563827/
https://www.ncbi.nlm.nih.gov/pubmed/32933155
http://dx.doi.org/10.3390/cells9092091

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