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Human Amnion Epithelial Cells Produce Soluble Factors that Enhance Liver Repair by Reducing Fibrosis While Maintaining Regeneration in a Model of Chronic Liver Injury

Human amnion epithelial cells (hAECs) exert potent antifibrotic and anti-inflammatory effects when transplanted into preclinical models of tissue fibrosis. These effects are mediated in part via the secretion of soluble factors by hAECs which modulate signaling pathways and affect cell types involve...

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Detalles Bibliográficos
Autores principales: Hodge, Alexander, Andrewartha, Neil, Lourensz, Dinushka, Strauss, Robyn, Correia, Jeanne, Goonetilleke, Mihiri, Yeoh, George, Lim, Rebecca, Sievert, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563845/
https://www.ncbi.nlm.nih.gov/pubmed/32813573
http://dx.doi.org/10.1177/0963689720950221