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Human Amnion Epithelial Cells Produce Soluble Factors that Enhance Liver Repair by Reducing Fibrosis While Maintaining Regeneration in a Model of Chronic Liver Injury
Human amnion epithelial cells (hAECs) exert potent antifibrotic and anti-inflammatory effects when transplanted into preclinical models of tissue fibrosis. These effects are mediated in part via the secretion of soluble factors by hAECs which modulate signaling pathways and affect cell types involve...
Autores principales: | Hodge, Alexander, Andrewartha, Neil, Lourensz, Dinushka, Strauss, Robyn, Correia, Jeanne, Goonetilleke, Mihiri, Yeoh, George, Lim, Rebecca, Sievert, William |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563845/ https://www.ncbi.nlm.nih.gov/pubmed/32813573 http://dx.doi.org/10.1177/0963689720950221 |
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