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Combined Methylome and Transcriptome Analyses Reveals Potential Therapeutic Targets for EGFR Wild Type Lung Cancers with Low PD-L1 Expression

SIMPLE SUMMARY: Low expression of programmed death-ligand 1 (PD-L1), epidermal growth factor receptor (EGFR) wild-type non-small cell lung cancer (NSCLCs) are refractory, and only few therapeutic options exist. This study aims to clarify the molecular basis of this special subtype of NSCLC and ident...

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Detalles Bibliográficos
Autores principales: Hu, Weilei, Wang, Guosheng, Yarmus, Lonny B., Wan, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563876/
https://www.ncbi.nlm.nih.gov/pubmed/32899191
http://dx.doi.org/10.3390/cancers12092496