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OTUB2 Promotes Homologous Recombination Repair Through Stimulating Rad51 Expression in Endometrial Cancer

Genetic instability, raised from dysregulation of DNA repair, is involved in tumor development. OTUB2 (ovarian tumor domain protease domain-containing ubiquitin aldehyde-binding protein 2), which is responsible for DNA double-strand break (DSB), is implicated in carcinogenesis of various tumors. The...

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Detalles Bibliográficos
Autores principales: Wan, Qiuyuan, Chen, Qing, Cai, Dongge, Zhao, Yan, Wu, Xiaoling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563931/
https://www.ncbi.nlm.nih.gov/pubmed/32830515
http://dx.doi.org/10.1177/0963689720931433