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Inhibition of post-trabeculectomy fibrosis via topically instilled antisense oligonucleotide complexes co-loaded with fluorouracil

Trabeculectomy is the mainstay of surgical glaucoma treatment, while the success rate was unsatisfying due to postoperative scarring of the filtering blebs. Clinical countermeasures for scar prevention are intraoperative intervention or repeated subconjunctival injections. Herein, we designed a co-d...

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Detalles Bibliográficos
Autores principales: Jiang, Kuan, Chen, Junyi, Tai, Lingyu, Liu, Chang, Chen, Xishan, Wei, Gang, Lu, Weiyue, Pan, Weisan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563997/
https://www.ncbi.nlm.nih.gov/pubmed/33088694
http://dx.doi.org/10.1016/j.apsb.2020.03.002