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Bispecific Chimeric Antigen Receptor T Cell Therapy for B Cell Malignancies and Multiple Myeloma

SIMPLE SUMMARY: In relapsed, refractory B cell malignancies and multiple myeloma, chimeric antigen receptor (CAR) T cell therapy has represented a major scientific advancement with high response rates and durable responses for many. Nonetheless, target antigen downregulation in tumor cells can lead...

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Detalles Bibliográficos
Autores principales: Cronk, Robert J., Zurko, Joanna, Shah, Nirav N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564024/
https://www.ncbi.nlm.nih.gov/pubmed/32899464
http://dx.doi.org/10.3390/cancers12092523