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Role of Jagged1-mediated Notch Signaling Activation in the Differentiation and Stratification of the Human Limbal Epithelium

The Notch signaling pathway plays a key role in proliferation and differentiation. We investigated the effect of Jagged 1 (Jag1)-mediated Notch signaling activation in the human limbal stem/progenitor cell (LSC) population and the stratification of the limbal epithelium in vitro. After Notch signali...

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Detalles Bibliográficos
Autores principales: González, Sheyla, Halabi, Maximilian, Ju, David, Tsai, Matthew, Deng, Sophie X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564045/
https://www.ncbi.nlm.nih.gov/pubmed/32842657
http://dx.doi.org/10.3390/cells9091945