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Functional Analysis of P450 Monooxygenase SrrO in the Biosynthesis of Butenolide-Type Signaling Molecules in Streptomyces rochei

Streptomyces rochei 7434AN4 produces two structurally unrelated polyketide antibiotics lankacidin and lankamycin, and their biosynthesis is tightly controlled by butenolide-type signaling molecules SRB1 and SRB2. SRBs are synthesized by SRB synthase SrrX, and induce lankacidin and lankamycin product...

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Detalles Bibliográficos
Autores principales:	Teshima, Aiko, Hadae, Nozomi, Tsuda, Naoto, Arakawa, Kenji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564063/ https://www.ncbi.nlm.nih.gov/pubmed/32854353 http://dx.doi.org/10.3390/biom10091237

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