FRET-Based Sorting of Live Cells Reveals Shifted Balance between PLK1 and CDK1 Activities During Checkpoint Recovery

Cells recovering from the G2/M DNA damage checkpoint rely more on Aurora A-PLK1 signaling than cells progressing through an unperturbed G2 phase, but the reason for this discrepancy is not known. Here, we devised a method based on a FRET reporter for PLK1 activity to sort cells in distinct populatio...

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Detalles Bibliográficos
Autores principales: Lafranchi, Lorenzo, Müllers, Erik, Rutishauser, Dorothea, Lindqvist, Arne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564076/
https://www.ncbi.nlm.nih.gov/pubmed/32961751
http://dx.doi.org/10.3390/cells9092126

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564076/
https://www.ncbi.nlm.nih.gov/pubmed/32961751
http://dx.doi.org/10.3390/cells9092126

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