Cargando…

DHA modulates MANF and TREM2 abundance, enhances neurogenesis, reduces infarct size, and improves neurological function after experimental ischemic stroke

AIMS: Mesencephalic astrocyte‐derived neurotrophic factor (MANF) is a secretory neurotrophic factor protein that promotes repair after neuronal injury. The microglia cell surface receptor (triggering receptor expressed on myeloid cells‐2; TREM2) regulates the production of pro‐ and antiinflammatory...

Descripción completa

Detalles Bibliográficos
Autores principales: Belayev, Ludmila, Hong, Sung‐Ha, Freitas, Raul S., Menghani, Hemant, Marcell, Shawn J., Khoutorova, Larissa, Mukherjee, Pranab K., Reid, Madigan M., Oria, Reinaldo B., Bazan, Nicolas G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564189/
https://www.ncbi.nlm.nih.gov/pubmed/32757264
http://dx.doi.org/10.1111/cns.13444