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DHA modulates MANF and TREM2 abundance, enhances neurogenesis, reduces infarct size, and improves neurological function after experimental ischemic stroke
AIMS: Mesencephalic astrocyte‐derived neurotrophic factor (MANF) is a secretory neurotrophic factor protein that promotes repair after neuronal injury. The microglia cell surface receptor (triggering receptor expressed on myeloid cells‐2; TREM2) regulates the production of pro‐ and antiinflammatory...
Autores principales: | Belayev, Ludmila, Hong, Sung‐Ha, Freitas, Raul S., Menghani, Hemant, Marcell, Shawn J., Khoutorova, Larissa, Mukherjee, Pranab K., Reid, Madigan M., Oria, Reinaldo B., Bazan, Nicolas G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564189/ https://www.ncbi.nlm.nih.gov/pubmed/32757264 http://dx.doi.org/10.1111/cns.13444 |
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