Triapine Derivatives Act as Copper Delivery Vehicles to Induce Deadly Metal Overload in Cancer Cells

Thiosemicarbazones continue to attract the interest of researchers as potential anticancer drugs. For example, 3-aminopyridine-2-carboxaldehyde thiosemicarbazone, or triapine, is the most well-known representative of this class of compounds that has entered multiple phase I and II clinical trials. T...

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Detalles Bibliográficos
Autores principales: Ohui, Kateryna, Stepanenko, Iryna, Besleaga, Iuliana, Babak, Maria V., Stafi, Radu, Darvasiova, Denisa, Giester, Gerald, Pósa, Vivien, Enyedy, Eva A., Vegh, Daniel, Rapta, Peter, Ang, Wee Han, Popović-Bijelić, Ana, Arion, Vladimir B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564244/
https://www.ncbi.nlm.nih.gov/pubmed/32961653
http://dx.doi.org/10.3390/biom10091336

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564244/
https://www.ncbi.nlm.nih.gov/pubmed/32961653
http://dx.doi.org/10.3390/biom10091336

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