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Triapine Derivatives Act as Copper Delivery Vehicles to Induce Deadly Metal Overload in Cancer Cells
Thiosemicarbazones continue to attract the interest of researchers as potential anticancer drugs. For example, 3-aminopyridine-2-carboxaldehyde thiosemicarbazone, or triapine, is the most well-known representative of this class of compounds that has entered multiple phase I and II clinical trials. T...
Autores principales: | Ohui, Kateryna, Stepanenko, Iryna, Besleaga, Iuliana, Babak, Maria V., Stafi, Radu, Darvasiova, Denisa, Giester, Gerald, Pósa, Vivien, Enyedy, Eva A., Vegh, Daniel, Rapta, Peter, Ang, Wee Han, Popović-Bijelić, Ana, Arion, Vladimir B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564244/ https://www.ncbi.nlm.nih.gov/pubmed/32961653 http://dx.doi.org/10.3390/biom10091336 |
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