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A Vaccine Displaying a Trimeric Influenza-A HA Stem Protein on Capsid-Like Particles Elicits Potent and Long-Lasting Protection in Mice

Due to constant antigenic drift and shift, current influenza-A vaccines need to be redesigned and administered annually. A universal flu vaccine (UFV) that provides long-lasting protection against both seasonal and emerging pandemic influenza strains is thus urgently needed. The hemagglutinin (HA) s...

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Detalles Bibliográficos
Autores principales: Thrane, Susan, Aves, Kara-Lee, Uddbäck, Ida E. M, Janitzek, Christoph M., Han, Julianna, Yang, Yuhe R., Ward, Andrew B., Theander, Thor G., Nielsen, Morten A., Salanti, Ali, Thomsen, Allan R., Christensen, Jan P., Sander, Adam F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564254/
https://www.ncbi.nlm.nih.gov/pubmed/32679905
http://dx.doi.org/10.3390/vaccines8030389