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A Vaccine Displaying a Trimeric Influenza-A HA Stem Protein on Capsid-Like Particles Elicits Potent and Long-Lasting Protection in Mice
Due to constant antigenic drift and shift, current influenza-A vaccines need to be redesigned and administered annually. A universal flu vaccine (UFV) that provides long-lasting protection against both seasonal and emerging pandemic influenza strains is thus urgently needed. The hemagglutinin (HA) s...
Autores principales: | Thrane, Susan, Aves, Kara-Lee, Uddbäck, Ida E. M, Janitzek, Christoph M., Han, Julianna, Yang, Yuhe R., Ward, Andrew B., Theander, Thor G., Nielsen, Morten A., Salanti, Ali, Thomsen, Allan R., Christensen, Jan P., Sander, Adam F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564254/ https://www.ncbi.nlm.nih.gov/pubmed/32679905 http://dx.doi.org/10.3390/vaccines8030389 |
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