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Signal Transduction Pathway Activity in High-Grade, Serous Ovarian Carcinoma Reveals a More Favorable Prognosis in Tumors with Low PI3K and High NF-κB Pathway Activity: A Novel Approach to a Long-Standing Enigma

SIMPLE SUMMARY: All cells have a complex internal network of ‘communication chains’ called signal transduction pathways (STPs). Through interaction of different proteins in STPs, they are partly responsible for the behavior of a cell. In our study, we investigated the activity of eight STPs in datas...

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Detalles Bibliográficos
Autores principales: van Lieshout, Laura, van de Stolpe, Anja, van der Ploeg, Phyllis, Bowtell, David, de Hullu, Joanne, Piek, Jurgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564278/
https://www.ncbi.nlm.nih.gov/pubmed/32961868
http://dx.doi.org/10.3390/cancers12092660