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Identification and Analysis of Unstructured, Linear B-Cell Epitopes in SARS-CoV-2 Virion Proteins for Vaccine Development

The efficacy of SARS-CoV-2 nucleic acid-based vaccines may be limited by proteolysis of the translated product due to anomalous protein folding. This may be the case for vaccines employing linear SARS-CoV-2 B-cell epitopes identified in previous studies since most of them participate in secondary st...

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Detalles Bibliográficos
Autores principales: Corral-Lugo, Andrés, López-Siles, Mireia, López, Daniel, McConnell, Michael J., Martin-Galiano, Antonio J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564417/
https://www.ncbi.nlm.nih.gov/pubmed/32698423
http://dx.doi.org/10.3390/vaccines8030397