Cargando…

Identification and Analysis of Unstructured, Linear B-Cell Epitopes in SARS-CoV-2 Virion Proteins for Vaccine Development

The efficacy of SARS-CoV-2 nucleic acid-based vaccines may be limited by proteolysis of the translated product due to anomalous protein folding. This may be the case for vaccines employing linear SARS-CoV-2 B-cell epitopes identified in previous studies since most of them participate in secondary st...

Descripción completa

Detalles Bibliográficos
Autores principales:	Corral-Lugo, Andrés, López-Siles, Mireia, López, Daniel, McConnell, Michael J., Martin-Galiano, Antonio J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564417/ https://www.ncbi.nlm.nih.gov/pubmed/32698423 http://dx.doi.org/10.3390/vaccines8030397

Ejemplares similares

Cross-Recognition of SARS-CoV-2 B-Cell Epitopes with Other Betacoronavirus Nucleoproteins
por: Tajuelo, Ana, et al.
Publicado: (2022)

Identification of Promoter Region Markers Associated With Altered Expression of Resistance-Nodulation-Division Antibiotic Efflux Pumps in Acinetobacter baumannii
por: López-Siles, Mireia, et al.
Publicado: (2022)

Predicted Epitope Abundance Supports Vaccine-Induced Cytotoxic Protection Against SARS-CoV-2 Variants of Concern
por: Martín-Galiano, Antonio J., et al.
Publicado: (2021)

Effect of Subinhibitory Concentrations of Antibiotics and Disinfectants on ISAba-Mediated Inactivation of Lipooligosaccharide Biosynthesis Genes in Acinetobacter baumannii
por: Olmeda-López, Héctor, et al.
Publicado: (2021)

Unsupervised Machine Learning Organization of the Functional Dark Proteome of Gram-Negative “Superbugs”: Six Protein Clusters Amenable for Distinct Scientific Applications
por: Sicilia, Carlos, et al.
Publicado: (2022)

Mutation Analysis in Regulator DNA-Binding Regions for Antimicrobial Efflux Pumps in 17,000 Pseudomonas aeruginosa Genomes
por: Pérez-Vázquez, María, et al.
Publicado: (2023)

Predicted impact of the viral mutational landscape on the cytotoxic response against SARS-CoV-2
por: Foix, Anna, et al.
Publicado: (2022)

Using Omics Technologies and Systems Biology to Identify Epitope Targets for the Development of Monoclonal Antibodies Against Antibiotic-Resistant Bacteria
por: Martín-Galiano, Antonio J., et al.
Publicado: (2019)

Role of peptidoglycan recycling enzymes AmpD and AnmK in Acinetobacter baumannii virulence features
por: Tajuelo, Ana, et al.
Publicado: (2023)

Identification of immunodominant linear epitopes from SARS-CoV-2 patient plasma
por: Farrera-Soler, Lluc, et al.
Publicado: (2020)

Subinhibitory Concentrations of Clinically-Relevant Antimicrobials Affect Resistance-Nodulation-Division Family Promoter Activity in Acinetobacter baumannii
por: Prieto Martin Gil, Sonia, et al.
Publicado: (2021)

Editorial: Resistant pathogens: from distribution to emerging therapies
por: García-Ríos, Estéfani, et al.
Publicado: (2023)

The immunodominant and neutralization linear epitopes for SARS-CoV-2
por: Lu, Shuai, et al.
Publicado: (2021)

Identification of B-Cell Linear Epitopes in the Nucleocapsid (N) Protein B-Cell Linear Epitopes Conserved among the Main SARS-CoV-2 Variants
por: Rodrigues-da-Silva, Rodrigo N., et al.
Publicado: (2023)

Identification of three conserved linear B cell epitopes on the SARS-CoV-2 spike protein
por: Wang, Aiping, et al.
Publicado: (2022)

Serodominant SARS-CoV-2 Nucleocapsid Peptides Map to Unstructured Protein Regions
por: Vandervaart, Jacob P., et al.
Publicado: (2023)

A promising inactivated whole-virion SARS-CoV-2 vaccine
por: Isakova-Sivak, Irina, et al.
Publicado: (2021)

Identification of conserved linear epitopes in the SARS-CoV-2 receptor-binding region using monoclonal antibodies
por: Yang, Yujie, et al.
Publicado: (2023)

SARS-CoV-2 Virion Stabilization by Zn Binding
por: Morante, Silvia, et al.
Publicado: (2020)

The total number and mass of SARS-CoV-2 virions
por: Sender, Ron, et al.
Publicado: (2021)

The total number and mass of SARS-CoV-2 virions
por: Sender, Ron, et al.
Publicado: (2021)

Linear systems with unstructured multiplicative uncertainty: Modeling and robust stability analysis
por: Matušů, Radek, et al.
Publicado: (2017)

Optimization of a Lambda-RED Recombination Method for Rapid Gene Deletion in Human Cytomegalovirus
por: García-Ríos, Estéfani, et al.
Publicado: (2021)

Protective Epitopes of the Plasmodium falciparum SERA5 Malaria Vaccine Reside in Intrinsically Unstructured N-Terminal Repetitive Sequences
por: Yagi, Masanori, et al.
Publicado: (2014)

BCEDB: a linear B-cell epitopes database for SARS-CoV-2
por: Tai, Chengzheng, et al.
Publicado: (2023)

The architecture of the SARS-CoV-2 RNA genome inside virion
por: Cao, Changchang, et al.
Publicado: (2021)

A multiscale coarse-grained model of the SARS-CoV-2 virion
por: Yu, Alvin, et al.
Publicado: (2021)

Brief Research Report: Virus-Specific Humoral Immunity at Admission Predicts the Development of Respiratory Failure in Unvaccinated SARS-CoV-2 Patients
por: Tajuelo, Ana, et al.
Publicado: (2022)

Effect of Inactivation Methods on SARS-CoV-2 Virion Protein and Structure
por: Loveday, Emma K., et al.
Publicado: (2021)

Corrigendum: Brief Research Report: Virus-Specific Humoral Immunity at Admission Predicts the Development of Respiratory Failure in Unvaccinated SARS-CoV-2 Patients
por: Tajuelo, Ana, et al.
Publicado: (2022)

Patterns of conserved gp120 epitope presentation on attached HIV-1 virions
por: Mengistu, Meron, et al.
Publicado: (2017)

Designing Multi-Antigen Vaccines Against Acinetobacter baumannii Using Systemic Approaches
por: McConnell, Michael J., et al.
Publicado: (2021)

Immunology to Immunotherapeutics of SARS-CoV-2: Identification of Immunogenic Epitopes for Vaccine Development
por: Pandey, Apoorva, et al.
Publicado: (2022)

Human neutralizing antibodies to cold linear epitopes and to subdomain 1 of SARS-CoV-2
por: Bianchini, Filippo, et al.
Publicado: (2022)

Identification of linear epitopes on the flagellar proteins of Clostridioides difficile
por: Razim, A., et al.
Publicado: (2021)

Particle Tracking on Unstructured Grids
por: Nelson, E M, et al.
Publicado: (2001)

Identification of two antigenic epitopes on SARS-CoV spike protein
por: Hua, Ronghong, et al.
Publicado: (2004)

Tapping into unstructured data: integrating unstructured data and textual analytics into business intelligence
por: Inmon, William H, et al.
Publicado: (2008)

Towards Control and Oversight of SARS‐CoV‐2 Diagnosis and Monitoring through Multiplexed Quantitative Electroanalytical Immune Response Biosensors
por: Torrente‐Rodríguez, Rebeca M., et al.
Publicado: (2022)

Towards Control and Oversight of SARS‐CoV‐2 Diagnosis and Monitoring through Multiplexed Quantitative Electroanalytical Immune Response Biosensors
por: Torrente‐Rodríguez, Rebeca M., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_r1eipemusuf3kdasqqnqooa4tv