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DNA Polymerase Alpha Subunit B Is a Binding Protein for Erlotinib Resistance in Non-Small Cell Lung Cancer

SIMPLE SUMMARY: Non-small-cell lung carcinoma (NSCLC) covers for almost 85% of all lung cancers and a major contributor to the overall cancer death rate. Erlotinib is used to treat NSCLC via inhibition of epithelial growth factor receptor (EGFR) kinase activity. Despite its high efficacy, recurrence...

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Detalles Bibliográficos
Autores principales: Kim, Tae Young, Ji, Eun Sun, Lee, Ju Yeon, Kim, Jin Young, Yoo, Jong Shin, Szasz, A. Marcell, Dome, Balazs, Marko-Varga, Gyorgy, Kwon, Ho Jeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564424/
https://www.ncbi.nlm.nih.gov/pubmed/32933200
http://dx.doi.org/10.3390/cancers12092613