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Calcium, Bioenergetics, and Parkinson’s Disease

Degeneration of substantia nigra (SN) dopaminergic (DAergic) neurons is responsible for the core motor deficits of Parkinson’s disease (PD). These neurons are autonomous pacemakers that have large cytosolic Ca(2+) oscillations that have been linked to basal mitochondrial oxidant stress and turnover....

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Detalles Bibliográficos
Autores principales: Zampese, Enrico, Surmeier, D. James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564460/
https://www.ncbi.nlm.nih.gov/pubmed/32911641
http://dx.doi.org/10.3390/cells9092045