Loss of ADAM9 Leads to Modifications of the Extracellular Matrix Modulating Tumor Growth

ADAM9 is a metalloproteinase strongly expressed at the tumor-stroma border by both tumor and stromal cells. We previously showed that the host deletion of ADAM9 leads to enhanced growth of grafted B16F1 melanoma cells by a mechanism mediated by TIMP1 and the TNF-α/sTNFR1 pathway. This study aimed to...

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Detalles Bibliográficos
Autores principales: Abety, Anna N., Pach, Elke, Giebeler, Nives, Fromme, Julia E., Aramadhaka, Lavakumar Reddy, Mauch, Cornelia, Fox, Jay W., Zigrino, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564588/
https://www.ncbi.nlm.nih.gov/pubmed/32906814
http://dx.doi.org/10.3390/biom10091290

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564588/
https://www.ncbi.nlm.nih.gov/pubmed/32906814
http://dx.doi.org/10.3390/biom10091290

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