Breast-Specific Epigenetic Regulation of DeltaNp73 and Its Role in DNA-Damage-Response of BRCA1-Mutated Human Mammary Epithelial Cells

The function of BRCA1/2 proteins is essential for maintaining genomic integrity in all cell types. However, why women who carry deleterious germline mutations in BRCA face an extremely high risk of developing breast and ovarian cancers specifically has remained an enigma. We propose that breast-spec...

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Detalles Bibliográficos
Autores principales: Avraham, Ayelet, Feldman, Susanna, Cho, Sean Soonweng, Kol, Ayala, Heler, Lior, Riklin-Nahmias, Emmanuela, Sella, Avishay, Karni, Tamar, Allweis, Tanir M., Sukumar, Saraswati, Evron, Ella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564633/
https://www.ncbi.nlm.nih.gov/pubmed/32825620
http://dx.doi.org/10.3390/cancers12092367

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564633/
https://www.ncbi.nlm.nih.gov/pubmed/32825620
http://dx.doi.org/10.3390/cancers12092367

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