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Multivalent and Bidirectional Binding of Transcriptional Transactivation Domains to the MED25 Coactivator
The human mediator subunit MED25 acts as a coactivator that binds the transcriptional activation domains (TADs) present in various cellular and viral gene-specific transcription factors. Previous studies, including on NMR measurements and site-directed mutagenesis, have only yielded low-resolution m...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564715/ https://www.ncbi.nlm.nih.gov/pubmed/32825095 http://dx.doi.org/10.3390/biom10091205 |