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Loganin Attenuates High Glucose-Induced Schwann Cells Pyroptosis by Inhibiting ROS Generation and NLRP3 Inflammasome Activation

Diabetic peripheral neuropathy (DPN) is caused by hyperglycemia, which induces oxidative stress and inflammatory responses that damage nerve tissue. Excessive generation of reactive oxygen species (ROS) and NOD-like receptor protein 3 (NLRP3) inflammasome activation trigger the inflammation and pyro...

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Detalles Bibliográficos
Autores principales: Cheng, Yu-Chi, Chu, Li-Wen, Chen, Jun-Yih, Hsieh, Su-Ling, Chang, Yu-Chin, Dai, Zen-Kong, Wu, Bin-Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564733/
https://www.ncbi.nlm.nih.gov/pubmed/32842536
http://dx.doi.org/10.3390/cells9091948