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Novel Caffeic Acid Phenethyl Ester-Mortalin Antibody Nanoparticles Offer Enhanced Selective Cytotoxicity to Cancer Cells

Caffeic acid phenethyl ester (CAPE) is a key bioactive ingredient of honeybee propolis and is claimed to have anticancer activity. Since mortalin, a hsp70 chaperone, is enriched in a cancerous cell surface, we recruited a unique cell internalizing anti-mortalin antibody (MotAb) to generate mortalin-...

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Detalles Bibliográficos
Autores principales: Wang, Jia, Bhargava, Priyanshu, Yu, Yue, Sari, Anissa Nofita, Zhang, Huayue, Ishii, Noriyuki, Yan, Kangmin, Zhang, Zhenya, Ishida, Yoshiyuki, Terao, Keiji, Kaul, Sunil C., Miyako, Eijiro, Wadhwa, Renu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564736/
https://www.ncbi.nlm.nih.gov/pubmed/32825706
http://dx.doi.org/10.3390/cancers12092370