Cargando…

Novel Caffeic Acid Phenethyl Ester-Mortalin Antibody Nanoparticles Offer Enhanced Selective Cytotoxicity to Cancer Cells

Caffeic acid phenethyl ester (CAPE) is a key bioactive ingredient of honeybee propolis and is claimed to have anticancer activity. Since mortalin, a hsp70 chaperone, is enriched in a cancerous cell surface, we recruited a unique cell internalizing anti-mortalin antibody (MotAb) to generate mortalin-...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Jia, Bhargava, Priyanshu, Yu, Yue, Sari, Anissa Nofita, Zhang, Huayue, Ishii, Noriyuki, Yan, Kangmin, Zhang, Zhenya, Ishida, Yoshiyuki, Terao, Keiji, Kaul, Sunil C., Miyako, Eijiro, Wadhwa, Renu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564736/ https://www.ncbi.nlm.nih.gov/pubmed/32825706 http://dx.doi.org/10.3390/cancers12092370

Ejemplares similares

Molecular Characterization and Enhancement of Anticancer Activity of Caffeic Acid Phenethyl Ester by γ Cyclodextrin
por: Wadhwa, Renu, et al.
Publicado: (2016)

Anticancer Activity in Honeybee Propolis: Functional Insights to the Role of Caffeic Acid Phenethyl Ester and Its Complex With γ-Cyclodextrin
por: Ishida, Yoshiyuki, et al.
Publicado: (2018)

A Low Dose Combination of Withaferin A and Caffeic Acid Phenethyl Ester Possesses Anti-Metastatic Potential In Vitro: Molecular Targets and Mechanisms
por: Sari, Anissa Nofita, et al.
Publicado: (2022)

Caffeic acid phenethyl ester (CAPE) confers wild type p53 function in p53(Y220C) mutant: bioinformatics and experimental evidence
por: Radhakrishnan, Navaneethan, et al.
Publicado: (2021)

Identification of a new member of Mortaparib class of inhibitors that target mortalin and PARP1
por: Meidinna, Hazna Noor, et al.
Publicado: (2022)

Relevance of mortalin to cancer cell stemness and cancer therapy
por: Yun, Chae-Ok, et al.
Publicado: (2017)

Identification of Caffeic Acid Phenethyl Ester (CAPE) as a Potent Neurodifferentiating Natural Compound That Improves Cognitive and Physiological Functions in Animal Models of Neurodegenerative Diseases
por: Konar, Arpita, et al.
Publicado: (2020)

Potential of Withaferin-A, Withanone and Caffeic Acid Phenethyl ester as ATP-competitive inhibitors of BRAF: A bioinformatics study
por: Malik, Vidhi, et al.
Publicado: (2021)

Computational Insights into the Potential of Withaferin-A, Withanone and Caffeic Acid Phenethyl Ester for Treatment of Aberrant-EGFR Driven Lung Cancers
por: Malik, Vidhi, et al.
Publicado: (2021)

Caffeic Acid Phenethyl Ester and Therapeutic Potentials
por: Murtaza, Ghulam, et al.
Publicado: (2014)

The Pluripotent Activities of Caffeic Acid Phenethyl Ester
por: Olgierd, Batoryna, et al.
Publicado: (2021)

Mortaparib, a novel dual inhibitor of mortalin and PARP1, is a potential drug candidate for ovarian and cervical cancers
por: Putri, Jayarani F., et al.
Publicado: (2019)

Identification and Characterization of Mortaparib(Plus)—A Novel Triazole Derivative That Targets Mortalin-p53 Interaction and Inhibits Cancer-Cell Proliferation by Wild-Type p53-Dependent and -Independent Mechanisms
por: Sari, Anissa Nofita, et al.
Publicado: (2021)

Combination of Withaferin-A and CAPE Provides Superior Anticancer Potency: Bioinformatics and Experimental Evidence to Their Molecular Targets and Mechanism of Action
por: Sari, Anissa Nofita, et al.
Publicado: (2020)

In vitro and in vivo neuroprotective effect of caffeic acid phenethyl ester
por: Akyol, Sumeyya, et al.
Publicado: (2015)

Bone resorption, matrix metalloproteinases and caffeic acid phenethyl ester
por: Akyol, Sumeyya, et al.
Publicado: (2016)

Targeting Mortalin by Embelin Causes Activation of Tumor Suppressor p53 and Deactivation of Metastatic Signaling in Human Breast Cancer Cells
por: Nigam, Nupur, et al.
Publicado: (2015)

Regulatory Effects of Caffeic Acid Phenethyl Ester on Neuroinflammation in Microglial Cells
por: Tsai, Cheng-Fang, et al.
Publicado: (2015)

Antiviral properties of caffeic acid phenethyl ester and its potential application
por: Erdemli, Hacı Kemal, et al.
Publicado: (2015)

Bioactivity and Chemical Synthesis of Caffeic Acid Phenethyl Ester and Its Derivatives
por: Zhang, Pengxuan, et al.
Publicado: (2014)

Caffeic Acid Phenethyl Ester Reduces the Adverse Effects of Nicotine on the Endometrium
por: Namdari, Amin, et al.
Publicado: (2023)

Why is Mortalin a Potential Therapeutic Target for Cancer?
por: Yoon, A-Rum, et al.
Publicado: (2022)

Use of caffeic acid phenethyl ester and cortisone may prevent proliferative vitreoretinopathy.
por: Turkoz, Yusuf, et al.
Publicado: (2004)

Caffeic Acid Phenethyl Ester Is a Potential Therapeutic Agent for Oral Cancer
por: Kuo, Ying-Yu, et al.
Publicado: (2015)

Value of Caffeic Acid Phenethyl Ester Pretreatment in Experimental Sepsis Model in Rats
por: Alici, Ozlem, et al.
Publicado: (2015)

Effects of caffeic acid phenethyl ester and melatonin on distraction osteogenesis: an experimental study
por: Erdem, Mehmet, et al.
Publicado: (2014)

Caffeic Acid Phenethyl Ester (CAPE): Biosynthesis, Derivatives and Formulations with Neuroprotective Activities
por: Pérez, Rebeca, et al.
Publicado: (2023)

The protective effect of caffeic acid phenethyl ester in the nephrotoxicity induced by α-cypermethrin
por: Nur, Gokhan, et al.
Publicado: (2023)

Experimental Evidence for Therapeutic Potentials of Propolis
por: Bhargava, Priyanshu, et al.
Publicado: (2021)

Caffeic acid phenethyl ester decreases acute pneumonitis after irradiation in vitro and in vivo
por: Chen, Miao-Fen, et al.
Publicado: (2005)

The effect of caffeic acid phenethyl ester on the functions of human monocyte-derived dendritic cells
por: Wang, Li-Chieh, et al.
Publicado: (2009)

Effects of caffeic acid phenethyl ester on palatal mucosal defects and tooth extraction sockets
por: Günay, Ahmet, et al.
Publicado: (2014)

Inhibitory Effects of Caffeic Acid Phenethyl Ester Derivatives on Replication of Hepatitis C Virus
por: Shen, Hui, et al.
Publicado: (2013)

Caffeic Acid Phenethyl Ester Regulates PPAR's Levels in Stem Cells-Derived Adipocytes
por: Vanella, Luca, et al.
Publicado: (2016)

Effect of caffeic acid phenethyl ester on bone formation in the expanded inter-premaxillary suture
por: Kazancioglu, Hakki Oguz, et al.
Publicado: (2015)

Protective Effects of Caffeic Acid Phenethyl Ester on Fluoxetine-Induced Hepatotoxicity: An Experimental Study
por: Yılmaz, Ahmet, et al.
Publicado: (2016)

Can propolis and caffeic acid phenethyl ester be promising agents against cyclophosphamide toxicity?
por: Akyol, Sumeyya, et al.
Publicado: (2016)

Synthesis and Biological Activity of Arylspiroborate Salts Derived from Caffeic Acid Phenethyl Ester
por: Hébert, Martin J. G., et al.
Publicado: (2015)

Protective Effects of Intralipid and Caffeic Acid Phenethyl Ester on Nephrotoxicity Caused by Dichlorvos in Rats
por: Celik, Muhammet Murat, et al.
Publicado: (2015)

Caffeic acid phenethyl ester promotes haematopoietic stem/progenitor cell homing and engraftment
por: Chen, Xiaofang, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_ipomjasjbf95nphu5dnpqafq7e