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A Systematic Review of Inverse Agonism at Adrenoceptor Subtypes

As many, if not most, ligands at G protein-coupled receptor antagonists are inverse agonists, we systematically reviewed inverse agonism at the nine adrenoceptor subtypes. Except for β(3)-adrenoceptors, inverse agonism has been reported for each of the adrenoceptor subtypes, most often for β(2)-adre...

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Detalles Bibliográficos
Autores principales: Michel, Martin C., Michel-Reher, Martina B., Hein, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564766/
https://www.ncbi.nlm.nih.gov/pubmed/32825009
http://dx.doi.org/10.3390/cells9091923