Breast Tumor Cell Invasion and Pro-Invasive Activity of Cancer-Associated Fibroblasts Co-Targeted by Novel Urokinase-Derived Decapeptides

Among peritumoral cells, cancer-associated fibroblasts (CAFs) are major facilitators of tumor progression. This study describes the effects of two urokinase-derived, novel decapeptides, denoted as Pep 1 and its cyclic derivative Pep 2. In a mouse model of tumor dissemination, using HT1080 fibrosarco...

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Detalles Bibliográficos
Autores principales: Belli, Stefania, Franco, Paola, Iommelli, Francesca, De Vincenzo, Anna, Brancaccio, Diego, Telesca, Marialucia, Merlino, Francesco, Novellino, Ettore, Ranson, Marie, Del Vecchio, Silvana, Grieco, Paolo, Carotenuto, Alfonso, Stoppelli, Maria Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564779/
https://www.ncbi.nlm.nih.gov/pubmed/32847144
http://dx.doi.org/10.3390/cancers12092404

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564779/
https://www.ncbi.nlm.nih.gov/pubmed/32847144
http://dx.doi.org/10.3390/cancers12092404

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