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Breast Tumor Cell Invasion and Pro-Invasive Activity of Cancer-Associated Fibroblasts Co-Targeted by Novel Urokinase-Derived Decapeptides
Among peritumoral cells, cancer-associated fibroblasts (CAFs) are major facilitators of tumor progression. This study describes the effects of two urokinase-derived, novel decapeptides, denoted as Pep 1 and its cyclic derivative Pep 2. In a mouse model of tumor dissemination, using HT1080 fibrosarco...
Autores principales: | Belli, Stefania, Franco, Paola, Iommelli, Francesca, De Vincenzo, Anna, Brancaccio, Diego, Telesca, Marialucia, Merlino, Francesco, Novellino, Ettore, Ranson, Marie, Del Vecchio, Silvana, Grieco, Paolo, Carotenuto, Alfonso, Stoppelli, Maria Patrizia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564779/ https://www.ncbi.nlm.nih.gov/pubmed/32847144 http://dx.doi.org/10.3390/cancers12092404 |
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