CCAAT/Enhancer-Binding Protein Delta (C/EBPδ): A Previously Unrecognized Tumor Suppressor that Limits the Oncogenic Potential of Pancreatic Ductal Adenocarcinoma Cells

SIMPLE SUMMARY: Here we show that a protein called C/EBPδ is present in healthy pancreas tissue but almost absent in pancreas tumors. Patients with less C/EBPδ in their tumors had the most metastases and the worst survival chances, showing that C/EBPδ has tumor-suppressive properties in pancreatic c...

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Detalles Bibliográficos
Autores principales: Hartl, Leonie, Duitman, JanWillem, Aberson, Hella L., Chen, Kan, Dijk, Frederike, Roelofs, Joris J.T.H., Dings, Mark P.G., Hooijer, Gerrit K.J., Hernanda, Pratika Y., Pan, Qiunwei, Busch, Olivier R., Besselink, Marc G.H., Boerman, Ton, Peppelenbosch, Maikel P., Bijlsma, Maarten F., Spek, C. Arnold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564797/
https://www.ncbi.nlm.nih.gov/pubmed/32906832
http://dx.doi.org/10.3390/cancers12092546

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564797/
https://www.ncbi.nlm.nih.gov/pubmed/32906832
http://dx.doi.org/10.3390/cancers12092546

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