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NRF2 Is an Upstream Regulator of MYC-Mediated Osteoclastogenesis and Pathological Bone Erosion

Osteoclasts are the sole bone-resorbing cells that play an essential role in homeostatic bone remodeling and pathogenic bone destruction such as inflammatory arthritis. Pharmacologically targeting osteoclasts has been a promising approach to alleviating bone disease, but there remains room for impro...

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Detalles Bibliográficos
Autores principales: Park, Peter Sang Uk, Mun, Se Hwan, Zeng, Steven L., Kim, Haemin, Bae, Seyeon, Park-Min, Kyung-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564846/
https://www.ncbi.nlm.nih.gov/pubmed/32967239
http://dx.doi.org/10.3390/cells9092133