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Lessons from Bacillus Calmette-Guérin: Harnessing Trained Immunity for Vaccine Development

Vaccine design traditionally focuses on inducing adaptive immune responses against a sole target pathogen. Considering that many microbes evade innate immune mechanisms to initiate infection, and in light of the discovery of epigenetically mediated innate immune training, the paradigm of vaccine des...

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Detalles Bibliográficos
Autores principales: Pasco, Samuel T., Anguita, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564904/
https://www.ncbi.nlm.nih.gov/pubmed/32948003
http://dx.doi.org/10.3390/cells9092109