Upregulation of DR5 and Downregulation of Survivin by IITZ-01, Lysosomotropic Autophagy Inhibitor, Potentiates TRAIL-Mediated Apoptosis in Renal Cancer Cells via Ubiquitin-Proteasome Pathway

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) selectively is able to increase apoptosis in cancer cells as agent with minimum toxicity to noncancerous cells. However, all cancer cells are not sensitive to TRAIL-induced apoptosis. In this study, we showed the sub-lethal concentratio...

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Detalles Bibliográficos
Autores principales: Shahriyar, Sk Abrar, Seo, Seung Un, Min, Kyoung-jin, Kubatka, Peter, Min, Do Sik, Chang, Jong-Soo, Kim, Dong Eun, Woo, Seon Min, Kwon, Taeg Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564912/
https://www.ncbi.nlm.nih.gov/pubmed/32825566
http://dx.doi.org/10.3390/cancers12092363

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564912/
https://www.ncbi.nlm.nih.gov/pubmed/32825566
http://dx.doi.org/10.3390/cancers12092363

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