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Evaluation of the Adverse Effects of Chronic Exposure to Donepezil (An Acetylcholinesterase Inhibitor) in Adult Zebrafish by Behavioral and Biochemical Assessments

Donepezil (DPZ) is an acetylcholinesterase inhibitor used for the clinical treatment of mild cognitive impairment. However, DPZ has been reported to have adverse effects, including causing abnormal cardiac rhythm, insomnia, vomiting, and muscle cramps. However, the existence of these effects in subj...

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Detalles Bibliográficos
Autores principales: Audira, Gilbert, Ngoc Anh, Nguyen Thi, Ngoc Hieu, Bui Thi, Malhotra, Nemi, Siregar, Petrus, Villalobos, Omar, Villaflores, Oliver B., Ger, Tzong-Rong, Huang, Jong-Chin, Chen, Kelvin H.-C., Hsiao, Chung-Der
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564914/
https://www.ncbi.nlm.nih.gov/pubmed/32962160
http://dx.doi.org/10.3390/biom10091340