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STAT3, the Challenge for Chemotherapeutic and Radiotherapeutic Efficacy

SIMPLE SUMMARY: STAT3, an oncogene, contributes to insensitivity of chemotherapy and radiotherapy in tumor, reduces the clinical efficacy. Meanwhile, STAT3β, a STAT3 splicing isoform, is related to the inhibition of tumor growth and chemosensitivity. STAT3 may become a potential target to overcome t...

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Detalles Bibliográficos
Autores principales: Yang, Ping-Lian, Liu, Lu-Xin, Li, En-Min, Xu, Li-Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564975/
https://www.ncbi.nlm.nih.gov/pubmed/32872659
http://dx.doi.org/10.3390/cancers12092459