Synthesis and Inhibitory Studies of Phosphonic Acid Analogues of Homophenylalanine and Phenylalanine towards Alanyl Aminopeptidases

A library of novel phosphonic acid analogues of homophenylalanine and phenylalanine, containing fluorine and bromine atoms in the phenyl ring, have been synthesized. Their inhibitory properties against two important alanine aminopeptidases, of human (hAPN, CD13) and porcine (pAPN) origin, were evalu...

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Detalles Bibliográficos
Autores principales: Wanat, Weronika, Talma, Michał, Dziuk, Błażej, Kafarski, Paweł
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565091/
https://www.ncbi.nlm.nih.gov/pubmed/32938014
http://dx.doi.org/10.3390/biom10091319

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565091/
https://www.ncbi.nlm.nih.gov/pubmed/32938014
http://dx.doi.org/10.3390/biom10091319

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