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Histidine Residues Are Responsible for Bidirectional Effects of Zinc on Acid-Sensing Ion Channel 1a/3 Heteromeric Channels

Acid-sensing ion channel (ASIC) subunits 1a and 3 are highly expressed in central and peripheral sensory neurons, respectively. Endogenous biomolecule zinc plays a critical role in physiological and pathophysiological conditions. Here, we found that currents recorded from heterologously expressed AS...

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Detalles Bibliográficos
Autores principales:	Jiang, Qian, Peterson, Andrew M., Chu, Yuyang, Yao, Xiaolan, Zha, Xiang-ming, Chu, Xiang-Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565092/ https://www.ncbi.nlm.nih.gov/pubmed/32887365 http://dx.doi.org/10.3390/biom10091264

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