Cargando…

Histidine Residues Are Responsible for Bidirectional Effects of Zinc on Acid-Sensing Ion Channel 1a/3 Heteromeric Channels

Acid-sensing ion channel (ASIC) subunits 1a and 3 are highly expressed in central and peripheral sensory neurons, respectively. Endogenous biomolecule zinc plays a critical role in physiological and pathophysiological conditions. Here, we found that currents recorded from heterologously expressed AS...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jiang, Qian, Peterson, Andrew M., Chu, Yuyang, Yao, Xiaolan, Zha, Xiang-ming, Chu, Xiang-Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565092/ https://www.ncbi.nlm.nih.gov/pubmed/32887365 http://dx.doi.org/10.3390/biom10091264

Ejemplares similares

Acid-Sensing Ion Channels and Mechanosensation
por: Ruan, Nina, et al.
Publicado: (2021)

The Role of Zinc in Modulating Acid-Sensing Ion Channel Function
por: Sun, Amber W., et al.
Publicado: (2023)

Commentary: Potential Therapeutic Consequences of an Acid-Sensing Ion Channel 1a-Blocking Antibody
por: Peterson, Andrew, et al.
Publicado: (2019)

Acid-Sensing Ion Channel 1 Contributes to Weak Acid-Induced Migration of Human Malignant Glioma Cells
por: Shah, Sareena, et al.
Publicado: (2021)

Acid-sensing ion channels are expressed in the ventrolateral medulla and contribute to central chemoreception
por: Song, Nana, et al.
Publicado: (2016)

Acid-sensing ion channels: trafficking and synaptic function
por: Zha, Xiang-ming
Publicado: (2013)

Acid-Sensing Ion Channel 2: Function and Modulation
por: Sivils, Andy, et al.
Publicado: (2022)

Acid-Sensing Ion Channels in Glial Cells
por: Cegielski, Victoria, et al.
Publicado: (2022)

A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain
por: Bohlen, Christopher J., et al.
Publicado: (2011)

Heteromeric TRP Channels in Lung Inflammation
por: Zergane, Meryam, et al.
Publicado: (2021)

Modeling the kinetics of heteromeric potassium channels
por: McGahan, Kees, et al.
Publicado: (2022)

A strategy for determining the equilibrium constants for heteromeric ion channels in a complex model
por: Benndorf, Klaus, et al.
Publicado: (2022)

Functional analyses of heteromeric human PIEZO1 Channels
por: Gnanasambandam, Radhakrishnan, et al.
Publicado: (2018)

Thermosensitive TRPV Channel Subunits Coassemble into Heteromeric Channels with Intermediate Conductance and Gating Properties
por: Cheng, Wei, et al.
Publicado: (2007)

Heteromeric Anopheline Odorant Receptors Exhibit Distinct Channel Properties
por: Pask, Gregory M., et al.
Publicado: (2011)

The S6 gate in regulatory Kv6 subunits restricts heteromeric K(+) channel stoichiometry
por: Pisupati, Aditya, et al.
Publicado: (2018)

Modulation of Ionotropic Glutamate Receptors and Acid-Sensing Ion Channels by Nitric Oxide
por: Wang, John Q., et al.
Publicado: (2012)

Acid-Sensing Ion Channel 2a (ASIC2a) Promotes Surface Trafficking of ASIC2b via Heteromeric Assembly
por: Kweon, Hae-Jin, et al.
Publicado: (2016)

How to Validate a Heteromeric Ion Channel Drug Target: Assessing Proper Expression of Concatenated Subunits
por: Sack, Jon T., et al.
Publicado: (2008)

Sensing with Ion Channels
por: Martinac, Boris
Publicado: (2008)

Histidine Scanning Mutagenesis of Basic Residues of the S4 Segment of the Shaker K(+) Channel
por: Starace, Dorine M., et al.
Publicado: (2001)

K Channel Subconductance Levels Result from Heteromeric Pore Conformations
por: Chapman, Mark L., et al.
Publicado: (2005)

Commentary: Slowing of the Time Course of Acidification Decreases the Acid-Sensing Ion Channel 1a Current Amplitude and Modulates Action Potential Firing in Neurons
por: William, Matthew, et al.
Publicado: (2021)

Oxygen sensing with ion channels
por: Kim, Donghee
Publicado: (2014)

Inhibition of Acid-Sensing Ion Channels by KB-R7943, a Reverse Na(+)/Ca(2+) Exchanger Inhibitor
por: Sun, Hua-Wei, et al.
Publicado: (2023)

Functional Characterization of Homo- and Heteromeric Channel Kinases TRPM6 and TRPM7
por: Li, Mingjiang, et al.
Publicado: (2006)

KCNQ2 and KCNQ5 form heteromeric channels independent of KCNQ3
por: Soh, Heun, et al.
Publicado: (2022)

Structure of a volume-regulated heteromeric LRRC8A/C channel
por: Rutz, Sonja, et al.
Publicado: (2022)

Enhancement of the Water Affinity of Histidine by Zinc and Copper Ions
por: Song, Yongshun, et al.
Publicado: (2022)

Preferential formation of human heteromeric SK2:SK3 channels limits homomeric SK channel assembly and function
por: Butler, Andrew S., et al.
Publicado: (2022)

Histidine Residue 94 Is Involved in pH Sensing by Histidine Kinase ArsS of Helicobacter pylori
por: Müller, Stefanie, et al.
Publicado: (2009)

Ion Channels and Zinc: Mechanisms of Neurotoxicity and Neurodegeneration
por: Morris, Deborah R., et al.
Publicado: (2012)

Acid-Sensing Ion Channels and Pain
por: Gu, Qihai, et al.
Publicado: (2010)

Acid-Sensing Ion Channels in Zebrafish
por: Montalbano, Giuseppe, et al.
Publicado: (2021)

Heteromeric Slick/Slack K(+) channels show graded sensitivity to cell volume changes
por: Tejada, Maria A., et al.
Publicado: (2017)

Bupropion Inhibits Serotonin Type 3AB Heteromeric Channels at Clinically Relevant Concentrations
por: Stuebler, Antonia G., et al.
Publicado: (2020)

Sensing through Non-Sensing Ocular Ion Channels
por: Kabra, Meha, et al.
Publicado: (2020)

The Drosophila nicotinic acetylcholine receptor subunits Dα5 and Dα7 form functional homomeric and heteromeric ion channels
por: Lansdell, Stuart J, et al.
Publicado: (2012)

Modification of potassium channel kinetics by histidine-specific reagents
Publicado: (1990)

The direct modulatory activity of zinc toward ion channels
por: Noh, Sujin, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_nua7jhl6idt70hg2ej7usilpn3