Clinical, Genomic, and Pharmacological Study of MYCN-Amplified RB1 Wild-Type Metastatic Retinoblastoma

SIMPLE SUMMARY: We present two cases of a subtype of retinoblastoma, a rare ocular tumor in children, presenting without the typical mutation in the RB1 gene but showing amplification of the transcription factor MYCN frequently reported in pediatric malignancies. Even though previous reports suggest...

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Detalles Bibliográficos
Autores principales: Zugbi, Santiago, Ganiewich, Daiana, Bhattacharyya, Arpita, Aschero, Rosario, Ottaviani, Daniela, Sampor, Claudia, Cafferata, Eduardo G., Mena, Marcela, Sgroi, Mariana, Winter, Ursula, Lamas, Gabriela, Suñol, Mariona, Daroqui, Manuel, Baialardo, Edgardo, Salas, Beatriz, Das, Anirban, Fandiño, Adriana, Francis, Jasmine H., Lubieniecki, Fabiana, Lavarino, Cinzia, Garippa, Ralph, Podhjacer, Osvaldo L., Abramson, David H., Radvanyi, François, Chantada, Guillermo, Llera, Andrea S., Schaiquevich, Paula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565107/
https://www.ncbi.nlm.nih.gov/pubmed/32971811
http://dx.doi.org/10.3390/cancers12092714

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565107/
https://www.ncbi.nlm.nih.gov/pubmed/32971811
http://dx.doi.org/10.3390/cancers12092714

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