A Mathematical Model of Average Dynamics in a Stem Cell Hierarchy Suggests the Combinatorial Targeting of Cancer Stem Cells and Progenitor Cells as a Potential Strategy against Tumor Growth

SIMPLE SUMMARY: Cancer stem cell (CSC) directed therapies have been increasingly developed during the last years. However, some reported experiments using this strategy showed that although delayed tumor growth was observed, the tumor was not completely eliminated. Here, we hypothesize that the simu...

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Detalles Bibliográficos
Autores principales: Molina-Peña, Rodolfo, Tudon-Martinez, Juan Carlos, Aquines-Gutiérrez, Osvaldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565144/
https://www.ncbi.nlm.nih.gov/pubmed/32932755
http://dx.doi.org/10.3390/cancers12092590

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565144/
https://www.ncbi.nlm.nih.gov/pubmed/32932755
http://dx.doi.org/10.3390/cancers12092590

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