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A Mathematical Model of Average Dynamics in a Stem Cell Hierarchy Suggests the Combinatorial Targeting of Cancer Stem Cells and Progenitor Cells as a Potential Strategy against Tumor Growth
SIMPLE SUMMARY: Cancer stem cell (CSC) directed therapies have been increasingly developed during the last years. However, some reported experiments using this strategy showed that although delayed tumor growth was observed, the tumor was not completely eliminated. Here, we hypothesize that the simu...
Autores principales: | Molina-Peña, Rodolfo, Tudon-Martinez, Juan Carlos, Aquines-Gutiérrez, Osvaldo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565144/ https://www.ncbi.nlm.nih.gov/pubmed/32932755 http://dx.doi.org/10.3390/cancers12092590 |
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