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Decreased Thymic Output Contributes to Immune Defects in Septic Patients

Background: Prolonged immunosuppression and hypoinflammation, termed compensatory anti-inflammatory response syndrome (CARS), contribute to high morbidity and mortality in the late phase of sepsis. Although apoptosis is a well-known cause of lymphopenia in sepsis, the contribution of thymic output t...

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Detalles Bibliográficos
Autores principales: Sommer, Natascha, Noack, Steffen, Hecker, Andreas, Hackstein, Holger, Bein, Gregor, Weissmann, Norbert, Seeger, Werner, Mayer, Konstantin, Hecker, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565146/
https://www.ncbi.nlm.nih.gov/pubmed/32825352
http://dx.doi.org/10.3390/jcm9092695