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Regulation of Poly(ADP-Ribose) Polymerase 1 Activity by Y-Box-Binding Protein 1

Y-box-binding protein 1 (YB-1) is a multifunctional positively charged protein that interacts with DNA or RNA and poly(ADP-ribose) (PAR). YB-1 is poly(ADP-ribosyl)ated and stimulates poly(ADP-ribose) polymerase 1 (PARP1) activity. Here, we studied the mechanism of YB-1-dependent PAR synthesis by PAR...

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Detalles Bibliográficos
Autores principales: Naumenko, Konstantin N., Sukhanova, Mariya V., Hamon, Loic, Kurgina, Tatyana A., Alemasova, Elizaveta E., Kutuzov, Mikhail M., Pastré, David, Lavrik, Olga I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565162/
https://www.ncbi.nlm.nih.gov/pubmed/32947956
http://dx.doi.org/10.3390/biom10091325