Natural Potent NAAA Inhibitor Atractylodin Counteracts LPS-Induced Microglial Activation

N-acylethanolamine-hydrolyzing acid amidase (NAAA) is a lysosomal enzyme that inhibits the degradation of palmitoylethanolamide (PEA), an endogenous lipid that induces analgesic, anti-inflammation, and anti-multiple sclerosis through PPARα activation. Only a few potent NAAA inhibitors have been repo...

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Detalles Bibliográficos
Autores principales: Yang, Longhe, Ji, Chunyan, Li, Yitian, Hu, Fan, Zhang, Fang, Zhang, Haiping, Li, Long, Ren, Jie, Wang, Zhaokai, Qiu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565389/
https://www.ncbi.nlm.nih.gov/pubmed/33117168
http://dx.doi.org/10.3389/fphar.2020.577319

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565389/
https://www.ncbi.nlm.nih.gov/pubmed/33117168
http://dx.doi.org/10.3389/fphar.2020.577319

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