The Efficacy of the Novel TSPO Ligands 2-Cl-MGV-1 and 2,4-Di-Cl-MGV-1 Compared to the Classical TSPO Ligand PK 11195 to Counteract the Release of Chemokines from LPS-Stimulated BV-2 Microglial Cells

The impact of ligands of the 18 kDa translocator protein (TSPO) on the release of chemokines is not vastly investigated. In the present study, we assessed the effect of our novel TSPO ligands 2-Cl-MGV-1 and 2,4-Di-Cl-MGV-1 compared to the classical TSPO ligand PK 11195 on chemokine release in LPS-st...

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Detalles Bibliográficos
Autores principales: Monga, Sheelu, Weizman, Abraham, Gavish, Moshe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565396/
https://www.ncbi.nlm.nih.gov/pubmed/32938018
http://dx.doi.org/10.3390/biology9090291

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565396/
https://www.ncbi.nlm.nih.gov/pubmed/32938018
http://dx.doi.org/10.3390/biology9090291

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